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Focusing on osteoporosis, oncology, narcolepsy and women’s health.

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15 communities simultaneously launched free osteoporosis clinics. HSN facilitates the “China’s osteoporosis experts’ opinions” them science popularization project

15 communities simultaneously launched free osteoporosis clinics. HSN facilitates the “China’s osteoporosis experts’ opinions” them science popularization project Osteoporosis is one of the serious social problems faced by the aging society. However, there are still many misunderstandings and gaps in the public’s understanding of it. On March 23, the “China’s osteoporosis experts’ opinions” science popularization project free clinic event was held simultaneously in 15 communities in 6 districts of Guangzhou, including Haizhu, Baiyun, Panyu, Huangpu, Yuexiu, and Liwan, benefiting nearly 10,000 residents. The event was hosted by Sun Yat-sen Memorial Hospital of Sun Yat-sen University. Nearly 50 medical staff and volunteers from the Department of Orthopedics and General Medicine of the hospital went deep into the community to screen the general public for osteoporosis using LINGLONG AI DXA Machines and provided them with professional bone health guidance. It is understood that this community free clinic, osteoporosis and fracture risk survey will be used as important data sources to form “China’s osteoporosis experts’ opinions” to help promote early detection, early diagnosis and early treatment of osteoporosis patients, and to promote the improvement of bone health of all citizens. Free clinical treatment held simultaneously in many communities and the research results will

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Awakening Dreams, Creating the Future – Expert Consultation on Pitolisant Hydrochloride Tablets for Narcolepsy

Narcolepsy is a globally recognized rare disease. In Asia, the prevalence rate of this condition is 0.0129% in Taiwan and 0.015% in South Korea. The peak age of onset in China is 8-12 years old. Currently, narcolepsy faces challenges such as low public awareness, low diagnosis rate and insufficient effective treatment drugs. “Tetralogy” is a common symptom of narcolepsy, which is very disturbing to life. (Tetralogy includes excessive daytime sleepiness, cataplexy attack, hypnagogic hallucination and sleep paralysis.) On June 30, 2023, Pitolisant Hydrochloride Tablets were approved in China for the treatment of adult narcolepsy indications. On December 13, 2023, Pitolisant Hydrochloride Tablets in two formulations were successfully included in the 2023 National Medical Insurance Negotiation Drug List. Pitolisant Hydrochloride Tablets are the world’s first H3 receptor antagonist/inverse agonist that increases the synthesis and release of the wakefulness-promoting neurotransmitter histamine in the brain by enhancing histaminergic neuron activity, thereby improving wakefulness and alertness in patients. From December 2023 to January 2024, the “Awakening Dreams, Creating the Future – Expert Consultation on Pitolisant Hydrochloride Tablets for Narcolepsy” was held in Guangzhou, Beijing and Shanghai. Renowned professors and experts from major hospitals in China participated, discussing guidelines interpretation, disease recognition, drug treatment and

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Provincial Platform Meeting Report: Multiple Provinces Held Special Academic Salons on Narcolepsy of Provincial Sleep Collaboration Group

To enhance the diagnosis and treatment of narcolepsy, promote exchanges and cooperation among medical units of provincial sleep coordination groups, and strengthen the construction of professional team of sleep disorders in sleep centers, HSN organized two special academic salons on narcolepsy in January 2024, covering more than 200 sleep experts from Shaanxi, Heilongjiang, Jilin and Liaoning provinces. The meeting of the provincial sleep collaboration group for the three northeastern provinces was held on January 26 via Tencent Meeting, with over 70 participants. Yang Yi, Vice President (Deputy Secretary) of the First Bethune Hospital of Jilin University, delivered the opening speech, and Professor Wang Zan chaired the meeting and lectured on Identification and Treatment of Narcolepsy, emphasizing the need of the disease for long-term medication, the disease’s threat to life safety, learning ability, economic burden and employment. He also pointed out low public awareness rate, long diagnosis time, and differential diagnosis of combined diseases. Through research, he shared the relieving effect of Pitolisant on tetralogy, and looked forward to the launch of Pitolisant. Professor Zhu Yulan from the 2nd Affiliated Hospital of Harbin Medical University explained the Interpretation of China’s Narcolepsy Guidelines 2022, emphasizing the first-tier recommendation status of Pitolisant. Professor

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LINGLONG AI DXA Machine Supports World Osteoporosis Day to Participate in Hospitals’ Free Clinical Treatment Nationwide.

Guangzhou TV Station Live Report: “LINGLONG” BMD Test: Prevention and Early Intervention are Key to Osteoporosis. October 20 every year is the World Osteoporosis Day. This date is set to raise public awareness of osteoporosis, promote the awareness that osteoporosis is preventable and treatable, reduce the risk of fractures in the elderly, and save families and the state from the huge economic and social burden caused by fractures. The China’s theme for World Osteoporosis Day 2023 was “Strong Muscles, Healthy Bones, Preventing and Treating Osteoporosis”. On this special day, HSN actively participated in hospitals’ free clinical treatment activities in multiple cities of China, including Beijing, Shanghai and Guangzhou, to screen for osteoporosis among the general public with LINGLONG AI DXA Machine. Photo of the Scene of Shanghai Sixth People’s Hospital Affiliated to Shanghai JiaoTong University Photo of the Scene of Nanfang Hospital Affiliated to Southern Medical University Photo of the Scene of Beijing Electric Power Hospital Osteoporosis is a common bone disease, especially prevalent among middle-aged and elderly people. This disease often occurs without obvious symptoms and is only discovered when a bone fracture occurs. Therefore, regular BMD test is an important means of prevention and early detection of osteoporosis.

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Go forward hand in hand to create brilliance RareStone & HSN Strategic Cooperation Press Conference

Go forward hand in hand to create brilliance RareStone & HSN Strategic Cooperation Press Conference October 20th, 2023 On October 18, 2023, RareStone Group (hereinafter referred to as RareStone) and Zhejiang Hesenna Medicine Co., Ltd. (hereinafter referred to as HSN) successfully held a strategic cooperation press conference in Guangzhou, and signed a national general agent contract for Wakix®! Mr.Xiang Yu, CEO of RareStone, Mr. Xun Zhimeng, vice president and head of Citrine Medicine, Mr. Zhang Shengjie, vice president and head of finance, and Mr. Cao Heng, director of business and supply chain; Ms. Li Shu, Chairman of HSN, Mr. Yan Amin, General Manager, Ms. Liang Jianhua, Deputy General Manager, Ms. Fu Lingxia, Marketing Director, and Mr. Chen Duowen, Project Director, attended the signing ceremony. At the beginning of the conference, CEO of RareStone, Mr. Xiang Yu and Vice President, Mr. Xun Zhimeng, together with Chairman of HSN, Ms. Li Shu and General Manager, Mr. Yan Amin, injected energy into the project at carefully selected auspicious moments to witness together the glorious moment when RareStone and HSN start their strategic cooperation! Mr. Xiang Yu, CEO of RareStone, and Ms. Li Shu, Chairman of HSN, signed a strategic cooperation agreement as representatives of both

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Theory and practice go hand in hand to build bone health

Guidelines for the Diagnosis and Treatment of Primary Osteoporosis” (2022) Interpretation Meeting Rocaltrol® City Tour·Beijing Station On July 20, 2023, the “Guidelines for the Diagnosis and Treatment of Primary Osteoporosis” (2022) Interpretation Meeting and Rocaltrol® City Tour” jointly organized by Pharmanovia & Hesenna was successfully held at the Inner Mongolia Hotel in Beijing. The original intention of the “City Tour” activity is to enhance the guiding role of the “Guidelines” for clinicians and promote the whole society to pay attention to the prevention and treatment of osteoporosis. We hope to use this activity to assist the Osteoporosis and Bone Mineral Disease Branch of the Chinese Medical Association to jointly Promote the standardized diagnosis and treatment of osteoporosis, strengthen the linkage between hospitals and doctors at all levels, and improve the treatment and rehabilitation of osteoporotic fractures. The meeting was co-chaired by Professor Li Mei from Peking Union Medical College Hospital, chairman-designate of the Osteoporosis and Bone Mineral Disease Branch of the Chinese Medical Association, and Professor Xue Qingyun, chief expert of the Department of Orthopedics from Beijing Hospital, chairman of the Bone and Joint Committee of the Chinese Health Care Medical Research Association. An experienced speaker introduced the updated content

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